|The project is aiming to create a comprehensive information resource for the functional analysis of pattern formation, tissue development and organogenesis. |
Whole-mount in situ hybridization on mid-gestation mouse embryos are used to assign genes to cell types and organs.
A genome wide screening for genes showing a tissue restricted expression pattern in mid-gestation embryos is performed to identify genes that are likely to play an important role in the regulatory networks controlling pattern formation and organogenesis.
The screening provides the basis for imaging the molecular anatomy of the mouse embryo, and for creating a gene resource for a directed functional analysis of developmental processes.